Tobey Maguire
Spider-Man / Peter Parker
Willem Dafoe
Green Goblin / Norman Osborn
Kirsten Dunst
Mary Jane Watson
James Franco
Harry Osborn
Cliff Robertson
Ben Parker
Rosemary Harris
May Parker
J.K. Simmons
J. Jonah Jameson
Joe Manganiello
Flash Thompson
Gerry Becker
Maximilian Fargas
Bill Nunn
Joseph 'Robbie' Robertson
Jack Betts
Henry Balkan
Stanley Anderson
General Slocum
Ron Perkins
Dr. Mendel Stromm
Michael Papajohn
Carjacker
K.K. Dodds
Simkins
Ted Raimi
Hoffman
Bruce Campbell
Ring Announcer
Elizabeth Banks
Miss Brant
John Paxton
Houseman
Tim DeZarn
Philip Watson
Taylor Gilbert
Madeline Watson
Randy Poffo
Bone Saw McGraw
Larry Joshua
Wrestling Promoter
Timothy Patrick Quill
Wrestling Arena Guard
Lisa Danielle
Bone-ette
Natalie T. Yeo
Bone-ette
Erica D. Porter
Bone-ette
Kristen Davidson
Bone-ette
Jason Padgett
Flash's Crony
Shan Omar Huey
Teacher
Sally Levi
Girl on Bus
Evan Arnold
Doctor
Jill Sayre
Nurse
Jim Ward
Project Coordinator
David Holcomb
Test Pilot
Octavia Spencer
Check-In Girl
Brad Grunberg
HecklerShane Habberstad
Little Billy
Deborah Wakeham
Billy's MomRachael Bruce
Times Square Child
Sam Raimi
Director
David Koepp
Screenplay
Danny Elfman
Original Music ComposerBernie Wrightson
Character DesignerTony Fanning
Art Direction
Avi Arad
Executive Producer
Ian Bryce
Producer
Arthur Coburn
Editor
Don Burgess
Director of Photography
Neil Spisak
Production Design
Francine Maisler
CastingKaren O'Hara
Set Decoration